Thieme Chemistry通过全面的奖励计划积极推动学术参与和卓越的研究。我们的学术奖项着重关注年轻研究人员，旨在表彰其早期成就并支持他们的独立研究生涯。

我们非常荣幸地揭晓2021年SYNTHESIS/SYNLETT最佳论文奖获得者！

来自德国慕尼黑的威斯特伐利亚大学的Ryan Gilmour教授及其团队获得2021年SYNTHESIS最佳论文奖。

Synthesis主编Mark Lautens教授评论道： 

“They describe a new way to access the heptafluoroisopropyl group, which is an emerging motif in drug discovery, agrochemistry and catalysis. Routes to fluorine-containing molecules continue to be of great interest in the design of functional small molecules. In this paper, the authors describe the use of a simple organocatalyst to promote the formal difluorination of α-trifluoromethyl-β-difluorostyrenes. A hypervalent iodine species, generated in situ, from Olah’s reagent and Selectfluor serves as the key catalytic species. An intriguing aspect of the work is the importance of A1,3 strain in determining the lowest-energy conformation of the product, which positions the benzylic C–F bond in alignment with the aryl ortho C–H group.”

来自美国加州大学欧文分校的Elizabeth R. Jarvo教授及其团队获得2021年SYNLETT最佳论文奖。

Synlett主编Benjamin List教授评论道： 

"In their brilliant work, Erika L. Lucas, Tristan M. McGinnis, Anthony J. Castro and Elizabeth R. Jarvo have invented a conceptually new approach to fluorinated cyclopropanes. It is based on a photocatalytic styrene methoxy difluoromethylation, the products of which are elegantly used in a nickel-catalyzed intramolecular cross-electrophile coupling reaction between the difluoromethyl moiety and the methyl ether. This work is highly creative and timely and an excellent example what SYNLETT readers can expect.”