HMR Issue 9/2023: 甲状腺乳头状癌 2023-09-21

Issue 09 · Volume 55 · September 2023

Hormone and Metabolic Research 2023年第9期现已上线,欢迎免费阅读本期三篇精选论文。

Original Article: Endocrine Care

Factors of Central Lymph Node Metastasis in Papillary Thyroid Cancer Based on C-TIRADS Analysis

Weijun Huang, Deli Chen, Minying Zhong, Jieyi Ye, Zhiyuan Zhi, Yanyan Xiao, Yuan Zhong


To study risk factors for central lymph node metastasis (CLNM) in papillary thyroid cancer (PTC) using the Chinese Thyroid Imaging Reporting and Data System (C-TIRADS). We retrospectively analysed patients who underwent PTC surgery and central lymph node dissection at First People’s Hospital of Foshan City. The clinical and ultrasonic data of the patients from 1150 cases were analysed by multivariate regression to evaluate the correlation between grayscale ultrasound (US) features, C-TIRADS score, and the classification of thyroid nodules and CLNM of PTCs...


Original Article: Endocrine Care

Association Between Papillary Thyroid Carcinoma and Vertebral Fracture

Hazuki Otani, Masakazu Notsu, Mika Yamauchi, Kiyoko Nawata, Keizo Kanasaki

Suppression of TSH levels associated with levothyroxine treatment is a known risk factor for fracture. However, it is unclear whether patients with papillary thyroid carcinoma (PTC) have a higher risk of vertebral fracture (VF) before TSH suppression. The aim of the study was to examine whether the risk of VF is higher in PTC than in healthy subjects. A hospital-based, matched case-control study was conducted comparing PTC and healthy individuals. We enrolled 43 postoperative patients with PTC scheduled for radioiodine therapy and 43 age- and sex-matched healthy controls...

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Original Article: Endocrine Care

Long-Term Efficacy and Safety of Recombinant Human Growth Hormone in Children Born Small for Gestational Age

Wei Wu, Chunxiu Gong, Yuchuan Li, Yuhua Hu, Haihong Gong, Junfen Fu, Ke Huang, Pin Li, Xiaoping Luo

华中科技大学, 北京儿童医院,江苏省人民医院,国家儿童健康与疾病临床医学研究中心,上海交通大学附属儿童医院

There is a lack of long-term data on the benefit of growth hormone (GH) treatment in Chinese children born small for gestational age (SGA). This study was conducted to assess the long-term efficacy and safety of GH treatment in children born SGA. One hundred and twenty prepubertal SGA children who did not achieve catch-up growth with height remained less than –2 standard deviations (SD) below gender-specific height were enrolled in this two-year, randomized, dose-comparative study followed by an extension study of up to 10 years. Daily subcutaneous injections of 0.23 mg/kg/week [low-dose (LD) group] or 0.46 mg/kg/week [high-dose (HD) group] somatropin were given for 104 weeks...

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