有机合成中的炔烃
Alkynes in Organic Synthesis
2026年09月24日，星期四
20:00 - 21:00 (北京时间）
本次由 Synlett 特别呈现的线上研讨会，将聚焦炔烃在现代有机合成中的卓越应用潜力。从铜氢催化（copper hydride catalysis）和炔酰胺（ynamide）化学，到金(I)卡宾中间体（gold(I) carbene intermediates）的生成与应用，本次研讨会将重点介绍该领域近年来令人瞩目的研究进展。
本次活动特邀多位领域知名学者带来精彩报告：
德国基尔大学
Synlett，副主编
会议主持
德国开姆尼茨工业大学
Coupling reactions based on copper hydride catalysis and alkynes
In this talk, H2-driven copper hydride chemistry with a special focus on transformations of alkynes will be discussed. Trapping of the key reactive intermediate, a vinylcopper(I) complex by either a proton (leading to an overall alkyne semihydrogenation) or with electrohiles/coupling partners will be presented. The latter pathway leads to atom efficient H2-driven carbon-carbon bond forming reactions catalyzed by a readily available 3d metal.
比利时布鲁塞尔自由大学
Harnessing the Unique Reactivity of Ynamides
Over the past two decades, the development of efficient and robust methods for their synthesis has transformed ynamides from scarcely studied “laboratory curiosities” into remarkably versatile reagents and building blocks for organic synthesis.
The distinctive electronic properties of their nitrogen-substituted triple bond endow ynamides with a unique reactivity profile that has enabled the development of a broad range of useful synthetic transformations. In particular, their finely tuned reactivity provides access to reaction pathways and molecular architectures that are difficult, or even impossible, to achieve with other classes of alkynes.
For almost two decades, our group has been actively involved in ynamide chemistry, from the development of synthetic strategies providing access to a broad variety of these compounds to the exploration and exploitation of their reactivity. This lecture will highlight selected contributions from our group, illustrating how the distinctive reactivity of ynamides can be harnessed to design new synthetic transformations and provide efficient access to structurally diverse and valuable molecular scaffolds.
西班牙加泰罗尼亚化学研究所
Gold(I) Carbenes from Alkynes
The synthetic applications of gold(I)-catalyzed reactions of acetylene gas involving gold(I) carbenes as key intermediates will be presented. In addition, other mechanistically novel transformations involving these highly electrophilic species will be discussed.
从铜氢催化到炔酰胺化学，再到金(I)卡宾化学，本期有机化学线上研讨会将带您深入了解炔烃在现代有机合成中的多样化应用及前沿进展。
