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Planta Medica | 全新天然药物研究内容精选 2023-03-06

Professors Kayser and Fürst's Highlights

您的早餐可能含有谷类食品和亚麻籽(称为 Linum usitatissimum),它们对您的健康有益。 人们对其植物雌激素活性知之甚少。这篇综述有助于对它有更好地理解,对木酚素、亚麻酸和其他衍生物进行了广泛的讨论,以探讨其对女性生殖状况的影响,对卵巢和卵巢细胞以及生殖激素的功能。这是一篇很好的综述,帮助我们更多地了解一种经典的药用植物,而我们认为我们对其了如指掌。

大麻素是众所周知的天然药物。我们大多数人把这个词与中性大麻素联系起来。事实是,它们中的大多数最初都是容易脱羧的羧酸衍生物。这种不稳定性是很棘手的。大多数时候,我们不知道这些羧基大麻素的模式和含量。作者们解决了这个问题,他们开发了一种基于现代GC-FID的可靠的检测和量化羧基类大麻素的技术。这不仅是植物化学研究的一个里程碑,也是代谢组学的一个里程碑。

欢迎阅读本期两篇精选论文。

Reviews

Influence of Flaxseed (Linum usitatissimum) on Female Reproduction

Alexander V. Sirotkin

This review describes the chemical composition of flaxseed (Linum usitatissimum) and its general health effects, as well as the currently available knowledge concerning its action on the female reproductive state, functions on the ovary and ovarian cells and reproductive hormones, as well as possible constituents and extra- and intracellular mediators mediating its effects on female reproductive processes. Flaxseed contains a number of biologically active molecules, which, acting through multiple signalling pathways, can determine numerous physiological, protective and therapeutic effects of flaxseed...

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Original article

Development and Validation of a GC-FID Method for the Quantitation of 20 Different Acidic and Neutral Cannabinoids

Waseem Gul, Elsayed A. Ibrahim, Sharjeel W. Gul, Iram Shahzadi, Mohamed M. Radwan, Suman Chandra, Hemant Lata, Mahmoud A. ElSohly

For decades, Cannabis sativa had been illegal to sell or consume around the world, including in the United States. However, in light of the recent 2018 Farm Bill and the legalization of hemp across the US, various cannabis preparations have flooded the market, making it essential to be able to quantitate the levels of the different acidic and neutral cannabinoids in C. sativa and to have a complete cannabinoid profile of the different chemovars of the cannabis plant...

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