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内分泌 | 2020年第11期主编精选论文 2020-11-30

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Experimental and 

Clinical Endocrinology & Diabetes

IMPACT FACTOR 2019: 2.058






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内分泌学期刊Experimental and Clinical Endocrinology & Diabetes 2020年第11期现已全新上线!

本刊主编为您精选来自Michaela Keuper等人的一篇综述,文章关注人类循环FGF21水平及其与疾病和临床参数的相关性,主要关注肥胖及其相关疾病,如2型糖尿病。欢迎您阅读全文。

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Circulating FGF21 Levels in Human Health and Metabolic Disease

Michaela KeuperHans-Ulrich HäringHarald Staiger

Human fibroblast growth factor 21 (FGF21) is primarily produced and secreted by the liver as a hepatokine. This hormone circulates to its target tissues (e. g., brain, adipose tissue), which requires two components, one of the preferred FGF receptor isoforms (FGFR1c and FGFR3c) and the co-factor beta-Klotho (KLB) to trigger downstream signaling pathways. In this review Keuper et al focus on circulating FGF21 levels in humans and their associations with disease and clinical parameters, focusing primarily on obesity and obesity-associated diseases such as type-2 diabetes.

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Experimental and Clinical Endocrinology & Diabetes

Issues per year : 12
Volume : 128
Year : 2020
ISSN : 0947-7349

本刊出版内分泌学和糖尿病学各个领域的优秀论文,从分子生物学到临床研究,它都是一个很好的资源。本刊最初以德文出版,自1983年英文版出版以来,知名度稳步提升,反映了其在这一领域的重要性。现在仍然是德语市场上历史最悠久的内分泌学期刊!

每期出版原创论文和简讯,以及针对当前主题的综述。此外,每年都会出版增刊,介绍国内和国际科学会议摘要或论文集。